Lipid-based nanoparticles represent a groundbreaking facet of nanomaterials and nanotechnology, seamlessly integrating molecular science with advanced delivery systems. Comprised of lipids, these nanoparticles are engineered with precision at the nanoscale to revolutionize drug delivery and therapeutic interventions. Within the domain of nanomaterials, lipid-based nanoparticles offer a versatile platform for encapsulating pharmaceutical agents, exhibiting the ability to encapsulate both hydrophobic and hydrophilic compounds. The amphiphilic nature of lipids allows for the formation of well-defined structures such as liposomes and lipid nanoparticles, providing efficient carriers for drug payloads. In the field of nanotechnology, these lipid-based nanoparticles showcase a remarkable ability to mimic biological membranes, enhancing their biocompatibility and interaction with biological systems. Their nanoscale dimensions enable targeted delivery of therapeutic compounds, minimizing side effects and optimizing efficacy. Furthermore, lipid-based nanoparticles play a pivotal role in overcoming challenges associated with poorly water-soluble drugs, enhancing their bioavailability through nanotechnology-enabled solutions. Tailorability is a key feature of lipid-based nanoparticles in nanomaterial design.
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Xinhua Ni, Guangzhou City University of Technology, China
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Chayanika Baishya, Indian Institute of Technology Guwahati, India